List of Drugs That Should NOT be Crushed or Chewed
January 9, 2010 in Nurses' Notes by isl30fvi3w
| Generic Name | Comments | |
| Accutane | isotretinoin | mucous membrane irritant |
| Acutrim | phenylpropanolamine | slow release |
| Adalat CC | nifedipine | slow release |
| Allerest 12 Hour | chlorpheniramine, phenylpropanolamine | slow release |
| Artane Sequels | trihexyphenydil | slow release; capsules may be opened and contents taken without chewing or crushing |
| Azulfidine Entabs | sulfasalazine | enteric coated |
| Bayer Extra Strength Enteric 500 | aspirin, enteric coated | enteric coated; slow release |
| Bayer Low Adult 81 mg | aspirin, enteric coated | enteric coated |
| Bayer Caplet | aspirin, enteric coated | enteric coated |
| Biphetamine | amphetamine, dextroamphetamine | slow release |
| Bisacodyl | bisacodyl | enteric coated |
| BiscoLax | bisacodyl | enteric coated |
| Bromfed, Bromfed-PD | brompheniramine, pseudoephedrine | slow release |
| Calan SR | verapamil | slow release |
| Cama Arthritis Strength | aspirin, magnesium oxide, aluminum hydroxide | special table formulation |
| Cardizem, Cardizem CD, Cardizem SR | diltiazem | slow release; capsules may be opened and contents taken without chewing or crushing |
| Chloral Hydrate | chloral hydrate | liquid-filled capsule |
| Chlor-Trimeton Repetab | chlorpheniramine | slow release |
| Choledyl SA | oxytriphylline | slow release |
| Compazine Spansule | prochlorperazine | slow release; capsules may be opened and contents taken without chewing or crushing |
| Constant T | theophylline | slow release; capsules may be opened and contents taken without chewing or crushing |
| Contac | chlorpheniramine, phenylpropanolamine | slow release; capsules may be opened and contents taken without chewing or crushing |
| Cotazym S | pancrelipase | enteric coated; capsules may be opened and contents taken without chewing or crushing |
| Covera-HS | verapamil | slow release |
| Deconamine SR | chlorpheniramine, pseudoephedrine | slow release |
| Depakene | valproic acid | slow release; mucous membrane irritant |
| Depakote | valproate disodium | enteric coated |
| Desoxyn Gradumets | methamphetamine | slow release |
| Dexatrim Max Strength | phenylpropanolamine | slow release |
| Dexatrim Max Strength | phenylpropanolamine | slow release |
| Dexedrine Spansule | dextroamphetamine | slow release |
| Diamox Sequels | acetazolamide | slow release |
| Dilacor XR | diltiazem | slow release |
| Dilatrate-SR | isosorbide dinitrate | slow release |
| Dimetane Extentab | brompheniramine, phenylephrine | slow release |
| Disophrol Chronotab | dexbrompheniramine, pseudoephedrine | slow release |
| Donnatol Extentab | atropine, scopolamine, hyoscyamine, phenobarbital | slow release |
| Donnazyme | pancreatin, pepsin, bile salts, atropine, scopolamine, hyoscyamine, phenobarbital | slow release |
| Drixoral | dexbrompheniramine, pseudoephedrine | slow release |
| Dulcolax | bisacodyl | enteric coated |
| Easprin | aspirin | enteric coated |
| Ecotrin | aspirin | enteric coated |
| E.E.S 400 | erythromycin ethylsuccinate | enteric coated |
| Elixophyllin SR | theophylline | slow release; capsules may be opened and contents taken without chewing or crushing |
| E-Mycin | erythromycin | enteric coated |
| Ergostat | ergotamine | sublingual tablet |
| Eryc | erythromycin | enteric coated; capsules may be opened and contents taken without chewing or crushing |
| Ery-tab | erythromycin | enteric coated |
| Erythrocin Stearate | erythromycin | enteric coated |
| Erythromycin Base | erythromycin | enteric coated |
| Eskalith CR | lithium | slow release |
| Fedahist Timecaps | chlorpheniramine, pseudoephedrine | slow release |
| Feldene | piroxicam | mucous membrane irritant |
| Feosol | ferrous sulfate | enteric coated |
| Feosol Spansule | ferrous sulfate | slow release; capsules may be opened and contents taken without chewing or crushing |
| Fergon | ferrous gluconate | slow release; capsules may be opened and contents taken without chewing or crushing |
| Ferro-Sequels | ferrous fumarate, docusate | slow release |
| Fero-Gradumet | ferrous sulfate | slow release |
| Festal II | pancrelipase | enteric coated |
| Glucotrol XL | glipizide | slow release |
| Gris-Peg | griseofulvin ultramicrosize | crushing may result in precipitation of drug as larger particles |
| Ilotycin | erythromycin | enteric coated |
| Inderal LA | propranolol | slow release |
| Inderide LA | propranolol, hydrochlorothiazide | slow release |
| Indocin SR | indomethacin | slow release; capsules may be opened and contents taken without chewing or crushing |
| Isoptin SR | verapamil | slow release |
| Isordil Tembid | isosorbide dinitrate | slow release |
| Iso-Bid | isosorbide dinitrate | slow release |
| Isosorbide dinitrate SR | isosorbide dinitrate | slow release |
| Isuprel Glossets | isoproterenol | sublingual |
| Kaon CL 10 | potassium chloride | slow release |
| Klor-Con | potassium chloride | slow release |
| Klotrix | potassium chloride | slow release |
| K-Tab | potassium chloride | slow release |
| Levsinex Timecaps | hyoscyamine | slow release |
| Lithobid | lithium | slow release |
| Meprospan | meprobamate | slow release; capsules may be opened and contents taken without chewing or crushing |
| Mestinon Timespan | pyridostigmine | slow release |
| Micro K | potassium chloride | slow release |
| MS Contin | morphine | slow release |
| Naldecon | phenylepherine, phenylpropanolamine, chlorpheniramine, phenyltoloxamine | slow release |
| Nico-400 | niacin | slow release |
| Nicobid | niacin | slow release |
| Nitro Bid | nitroglycerin | slow release; capsules may be opened and contents taken without chewing or crushing |
| Nitroglyn | nitroglycerin | slow release; capsules may be opened and contents taken without chewing or crushing |
| Nitrong SR | nitroglycerin | slow release |
| Nolamine | phenylpropanolamine, chlorpheniramine, phenindamine | slow release |
| Norflex | orphenadrine | slow release |
| Norpace CR | disopyramide | slow release |
| Novafed A | pseudoephedrine, chlorpheniramine | slow release |
| Oramorph SR | morphine | slow release |
| Ornade Spansule | phenylpropanolamine, chlorpheniramine | slow release |
| Pancrease | pancrelipase | enteric coated |
| Papaverine Sustained Action | papaverine | slow release |
| Pavabid | papaverine | slow release |
| Pavabid Plateau | papaverine | slow release; capsules may be opened and contents taken without chewing or crushing |
| PBZ-SR | tripelennamine hydrochloride | slow release |
| Perdiem | psyllium hydrophilic mucioid | wax coated |
| Peritrate SA | pentaerythritol tetranitrate | slow release |
| Permitil Chronotab | fluphenazine | slow release |
| Phazyme, Phazyme 95 | simethicone | slow release |
| Phyllocontin | aminophylline | slow release |
| Plendil | felodipine | slow release |
| Polaramine Repetabs | dexchlorpheniramine | slow release |
| Prevacid | lansoprazole | slow release; capsules may be opened and contents taken without chewing or crushing |
| Prilosec | omeprazole | slow release |
| Procainamide HCl SR | procainamide | slow release |
| Procan SR | procainamide | slow release |
| Procardia XL | nifedipine | slow release |
| Pronestyl SR | procainamide | slow release |
| Proventil Repetabs | albuterol | slow release |
| Prozac | fluoxetine | slow release; capsules may be opened and contents taken without chewing or crushing |
| Quibron-T SR | quinidine gluconate | slow release |
| Quinaglute Dura Tabs | quinidine gluconate | slow release |
| Quinidex Extentabs | quinidine sulfate | slow release |
| Respid | theophylline | slow release |
| Ritalin SR | methylphenidate | slow release |
| Robimycin Robitab | erythromycin | enteric coated |
| Rondec TR | pseudoephedrine, carbinoxamine | slow release |
| Roxanol SR | morphine | slow release |
| Sinemet CR | levodopa, carbidopa | slow release; tablet is scored and may be broken in half |
| Slo-Bid Gyrocaps | theophylline | slow release; capsules may be opened and contents taken without chewing or crushing |
| Slo-Phyllin Gyrocaps | Slo-Phyllin theophylline | slow release; capsules may be opened and contents taken without chewing or crushing |
| Slow-Fe | ferrous sulfate | slow release |
| Slow-K | potassium chloride | slow release |
| Sorbitrate SA | isosorbide dinitrate | slow release |
| Sudafed 12 hour | pseudoephedrine | slow release |
| Tavist-D | phenylpropanolamine, clemastine | multiple compressed tablet |
| Teldrin | chlorpheniramine | slow release; capsules may be opened and contents taken without chewing or crushing |
| Tepanil Ten-Tab | diethylpropion | slow release |
| Tessalon Perles | benzonatate | slow release |
| Theo-24 | theophylline | slow release |
| Theobid, Theobid Jr. | theophylline | slow release |
| Theo-Dur | theophylline | slow release |
| Theo-Dur Sprinkle | theophylline | slow release; capsules may be opened and contents taken without chewing or crushing |
| Theolair SR | theophylline | slow release |
| Thorazine Spansule | chlorpromazine | slow release |
| Toprol XL | metaprolol | slow release |
| Trental | pentoxifylline | slow release |
| Triaminic | phenylpropanolamine, chlorpheniramine | enteric coated |
| Triaminic 12 | phenylpropanolamine, chlorpheniramine | slow release |
| Triaminic TR | phenylpropanolamine, pyrilamine, pheniramine | multiple compressed tablet |
| Trilafon Repetabs | perphenazine | slow release |
| Triptone Caplets | scopolamine | slow release |
| Uniphyl | theophylline | slow release |
| Valrelease | diazepam | slow release |
| Verelan | verapamil | slow release; capsules may be opened and contents taken without chewing or crushing |
| Volmax | albuterol | slow release |
| Welbutrin SR | bupropion | bupropion |
| Wyamycin S | erythromycin stearate | erythromycin stearate |
| ZORprin | aspirin | slow release |

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